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Thomas Letzel discusses the latest trends in non-targeted screening and chromatography.

A new validated liquid chromatography–mass spectrometry (LC–MS) protocol for acrylamide (AA) detection in infant formula was developed using sequential hydration, acetonitrile (ACN) precipitation, and dual-sorbent clean-up, which minimized matrix effects and ensured clarity and high reproducibility.

Top articles published this week includes a deep dive into our chromatography industry survey results. and an exploration on the evolution of peptide science and modern technology.

Brett Paull explores the latest trends in chromatography, with a focus on portable LC instruments and miniaturization.

Dave Bell explores the latest trends in chromatography, with a focus on miniaturization and green technologies.

Researchers identified two novel selenium-containing peptides from selenium-enriched oysters that strongly inhibit ACE, improve vascular function, and outperform captopril in vitro, highlighting their promise as natural antihypertensive ingredients.

Tony Edge explores 2026 trends in chromatography, highlighting the impact of AI and automation on the industry.

Velaris has acquired Markes International from Schauenburg International, strengthening its automated sample preparation portfolio, expanding its global presence, and enhancing support for laboratories across multiple end markets.

A recent study investigated the nutritional composition, bioactive compounds, and in vitro rumen fermentation characteristics of two tropical seaweeds, brown seaweed (Sargassum binderi) and green seaweed (Kappaphycus striatum), as potential functional feed additives for ruminant livestock profiled amino acids and fatty acids using HPLC and GC-FID, respectively.

To characterize the per- and polyfluoroalkyl substance (PFAS) content and migration potential of winter gloves and conduct a screening-level risk assessment of perfluorooctanoic acid (PFOA) and perfluorohexanoic acid (PFHxA) glove exposures in children aged 2-6 (considering both hand-to-mouth transfer and dermal absorption), experimental data were generated through total fluorine analysis, liquid chromatography–tandem mass spectrometry (LC–MS/MS), gas chromatography–tandem mass spectrometry (GC–MS/MS), and leachate testing of individual glove components across eight glove brands.

A review of some of the content highlights from LCGC International in 2025.

Research conducted by the Department of Food Science and Technology of Oregon State University and the Legacy Research Institute of Dow Neurobiology addressed this gap by developing a standardized aroma lexicon and associated sensory methodology, supported by GC-MS analysis of terpenes and terpenoids plus GC-PFPD analysis of volatile sulfur compounds. LCGC International spoke to Thomas H. Shellhammer of Oregon State University about this work.

In its 2025 industry survey, LCGC International looked beyond the numbers to uncover the challenges, priorities, and outlook shaping the chromatography community, and what lies ahead in 2026.